French authorities said on Tuesday morning that the two suspects had been charged with the murder of Knoll facing charges of "murder related to the victim's religion, real or imagined" as well as aggravated robbery and destruction of property.
Although their names have not been released, French authorities do say they have two suspects in custody, ages 22 and 29.
Knoll managed to avoid the notorious 1942 roundup of more than 13,000 Jews in Paris by fleeing with her mother to Portugal when she was 10. After the war, she returned to France and married a Holocaust survivor, who is now deceased. A smell of smoke still lingered in the air. "And then, she was an 85-year-old lady who had lived her life trying to make the most out of what life could give her because she had suffered during the war. We offer our profound condolences to the family of Mireille Knoll". Politicians across the political spectrum pledged to attend.
The most recent figures available show that anti-Semitic violence increased by 26 percent a year ago in France and that criminal damage to Jewish places of worship and burials increased by 22 percent. In a recent speech at a CRIF event, President Macron expressed satisfaction that the crime was being tried as an anti-Semitic attack.
"I reaffirm my absolute determination to fight against anti-Semitism", he wrote on Twitter.
"To survive the Holocaust, only to be brutally attacked and murdered at age 85 for being Jewish is beyond cruel".
Tensions around the Israeli-Palestinian conflict, as well as anti-Semitic propaganda by some Islamist preachers and media, are widely seen as playing a role.
France's chief rabbi on Monday described Knoll's death as a "horror" and Jewish leaders called for a march in her memory. According to a source close to the investigation, the first autopsy found stab wounds on the victim's body.
The French Interior Ministry recorded 311 anti-Semitic incidents in 2017, down from 335 in 2016 and 800 in 2015.
"There have been 11 anti-Semitic murders since 2000 and added to that there is all the everyday violence that the Jewish community goes through".
On Sunday, a spokesperson for SPCJ, the official monitor and security unit of the French Jewish community, told the 7sur7 news website that a preliminary examination of the crime "does not reveal an anti-Semitic characteristic, but this possibility has not been discounted as police investigate further". Speaking during an official visit to Israel, Le Drian said that "it was a very hard and emotional moment for me".