Dec joked at the start of tonight's show saying: "We have got a jam-packed show, this week we have lots to cram in and twice the amount of work to do".
But he will feature in the episode as part of the duo's pre-recorded Saturday Knight Takeaway sketch after it was decided they should be broadcast.
"@SamdySonxxxxx posted: "@antanddec @itvtakeaway Dec you did yourself & Ant proud, it was a fabulous but emotional show, keep smiling. looking forward to next week".
Ant McPartlin appeared to have been edited out of the trailer for Ant & Dec's Saturday Night Takeaway finale.
Paloma Faith was on hand to perform a couple of tracks during the show, while guest announcer Stephen Merchant, and regular contributors Stephen Merchant and Scarlett Moffatt also helped out.
Hours before the live show, the programme's official Twitter account previewed the script which confirmed Dec would be hosting alone.
@Mitchinator9339 wrote on Twitter: "Dec did such a good job on #SaturdayNightTakeaway tonight".
Saturday Night Takeaway was cancelled the week after Ant's auto accident, but the show returned for Easter weekend.
The 42-year-old presenter will also present next week's episode, the final one in the current series from Florida.
The TV star failed a breathalyser test and was taken to a local police station; he was charged with drink-driving three days later.
'Hello and a very warm welcome to all Virgin Holiday customers heading to - Orlando!' she tells passengers as confetti explodes around her, adding: 'OK, I know that yous are all excited but just hold on a little bit, please'.