While Samsung Electronics, the world's largest manufacturer of chips and smartphones and the flagship company of the group, have not said how the investment will be distributed.
Samsung expected to create 40,000 new jobs, including generating up to 20,000 additional new jobs on top of the previous hiring plans, over the next three years.
Samsung and its affiliated companies plan to spend $US22 billion ($A30 billion) over the next three years on artificial intelligence, auto components and other future businesses.
Samsung said it will also bolster its mainstay chip business, which is already the major source of profit for the company.
Samsung has been one of the most profitable tech companies on the planet in recent years.
It plans to attract more than 1,000 talents into its AI research lab in Korea; secure leadership in the 5G network-related equipment and device market; and speed up its automotive parts business for connected cars, including driverless vehicles.
In the field of artificial intelligence, Samsung hopes to take its researcher base beyond the 1,000 mark across it global AI Centres.
Samsung said most of the new investments will be injected in its key businesses such as semiconductors and displays in order to develop value-added premium products and further widen gaps with runner-ups, especially those of China.
"Samsung has seen strong growth from both its contract manufacturing and biosimilar businesses".
Vice-chairman Mr Lee met Mr Moon at the Indian factory's opening this year, his first meeting with the nation's leader since Mr Lee was released in February on a suspended jail sentence for a graft conviction.
The announcement sent shares in Samsung's contract drugmaker Biologics and in its IT affiliate SDS up five per cent. Samsung Electronics' share price closed this morning flat.
The three-year investment plan, announced shortly after Samsung Electronics Co.