Lula is now serving a 12-year prison sentence for graft and money laundering.
But barring dramatic events - the judges can reconsider their decision after the vote of the last two magistrates - the former president, who is best known as Lula, cannot run for a third term.
Brazil's top electoral court will open debate on Friday afternoon whether jailed former president Luiz Inacio Lula da Silva should be barred from running in this year's presidential election due to a corruption conviction.
He said the Workers' Party should replace da Silva in up to 10 days and said he should not appear as a presidential candidate in free airtime that is given to political parties on nationwide TV and radio starting on Saturday. Lula had been the Workers' Party nominee for the presidential elections set for October.
A party statement said the court had bowed to the wishes of Brazil's elites to stop Lula returning to office.
A majority of Brazil's top electoral court shot down late Friday the candidacy of popular leftist Luiz Inacio Lula da Silva in the country's upcoming presidential vote, telling the jailed former leader he can not participate in October's critical election.
Justice Edson Fachin disagreed, citing a recent call by a United Nations human rights committee calling for Lula to be allowed to run while he further appeals his conviction.
A driver shows a small doll depicting Brazil's Former President Luiz Inacio Lula da Silva, while making the "L" hand sign for Lula, during a protest in front of the Superior Electoral Tribunal, as the trial against the candidacy of the jailed former president continues, in Brasilia, Brazil, Friday, Aug. 31, 2018.
He was found guilty in July 2017 and then lost his first appeal in January.
He vehemently denies the accusations and has dismissed the charges as a political plot aimed at preventing him from standing in the elections.
The former leader's attorneys still hope to get the ban overturned by appealing the decision before Brazil's supreme court.
Vice-presidential running mate Fernando Haddad, a former mayor of Sao Paulo, is expected to head the ticket hoping to inherit the bulk of Lula's votes. His nearest rival, far-right candidate Jair Bolsonaro, has 19 percent.
But he is adored by millions of Brazilians due to the prosperity Brazil enjoyed under his leadership from 2003 to 2010. But whether Lula can transfer his popularity to a replacement remains to be seen.